Welcome to the Bashor Lab
A link to the Bashor lab Instagram
Interested in doing synthetic biology in Houston? Come join us!
Synthetic Biology at Rice University
What We Do: The goal of our work is to use synthetic regulatory circuits to reprogram the behavior of human cells.
Our Research
The Bashor Lab
Using the tools of synthetic biology, we construct artificial regulatory circuits and test their function in living cells. This not only gives us insight into the design logic of natural regulation, but also allows us to predictably alter cellular phenotype to create cell-based translational applications.
Publications
Yang X, Her J, Bashor CJ (2019). Mammalian signaling circuits from bacterial parts. Nature Chemical Biology,
Heins ZJ, Mancuso CP, Kiriakov S, Wong BG, Bashor CJ, Khalili AS (2019). Designing automated, high-throughput, continuous cell growth experiments using eVOLVER. Journal of Visualized Experiments. 147: e59652
O'Connell RW, Bashor CJ (2019) The least mating pathway: synthetically refactoring a familiar signaling system for new applications. Cell. 177:521-3
Bashor CJ, Patel N, Choubey S, Beyzavi A, Kondev J, Collins JJ, Khalil AS (2019). Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies. Science. 364(6440): 593-7.
Perspective by Andrew H. Ng & Hana El-Samad in Science 363(6440): 531-2
Perspective by Andrew H. Ng & Hana El-Samad in Science 363(6440): 531-2
Wong BG, Mauso CP, Kiriakov S, Bashor CJ, Khalil AS. (2018) Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER. Nature Biotechnology. 36(7): 614-23
Technology Feature by Mike May in Nature 569: 587-8
Bashor CJ, Collins JJ. (2018) Understanding biological regulation through synthetic biology. Annual Review of Biophysics. 47: 399-423
John Her
PhD Student - Bioengineering
B.S. Chemical Engineering, University of California, Berkeley
Ronan O'Connell
PhD Student - Bioengineering
MEng Biomedical Engineering, The University of Glasgow, Scotland
Trenton Piepergerdes
PhD Student - Bioengineering
M.S. Bioengineering, Rice University
B.S. Biomedical Engineering, Vanderbilt University
Lucas Brown
PhD Student - Systems, Synthetic, and Physical Biology
B.S. Biochemistry, Tufts University
B.S. Biotechnology, Tufts University
Xiaoyu Yang
PhD Student - Systems, Synthetic, and Physical Biology
B.S. Life Science, Peking University
Abram Qui
Undergraduate - Bioengineering
B.S.B. Bioengineering, Rice University,
In Progress
Olivia Frasher
PhD Student - Systems, Synthetic, and Physical Biology
B.S. Chemical Engineering, University of Notre Dame
Tawan (Pop) Kiratiwongwan
PhD Student - Bioengineering
B.BmE. Bioengineering, University of Minnesota
Zheng Diao
PhD Student - Systems, Synthetic, and Physical Biology
B.S. Biochemistry, University of Minnesota
Alena Streletskaia
PhD Student - BioSciences
B.S./M.S. Pharmaceutical Sciences, Lomonosov Moscow State University
Kshitij Rai
PhD Student - Systems, Synthetic, and Physical Biology
B.Eng/M.Eng Biochemical Engineering and Biotechnology , Indian Institute of Technology (IIT) Delhi
AJ Walters
PhD Student - Bioengineering
B.S. Biological/Biosystems Engineering, Utah State University
Shonik Ganjoo
Undergraduate - Bioengineering
In Progress
Bioengineering, Rice University
Kian Samra
Undergraduate - Bioengineering
In Progress
Bioengineering, Rice University
Vicky Liu
Undergraduate - Bioengineering
In Progress
Bioengineering, Rice University
Caleb Bashor
Principle Investigator
Post Doc, MIT
Ph.D Biophysics, UCSF
B.A. Biochemistry, Reed College