Welcome to the Bashor Lab
A link to the Bashor lab Instagram
Interested in doing synthetic biology in Houston? Come join us!
Synthetic Biology at Rice University
What We Do: The goal of our work is to use synthetic regulatory circuits to reprogram the behavior of human cells.
Our Research
The Bashor Lab
Using the tools of synthetic biology, we construct artificial regulatory circuits and test their function in living cells. This not only gives us insight into the design logic of natural regulation, but also allows us to predictably alter cellular phenotype to create cell-based translational applications.
Publications
Yang X, Her J, Bashor CJ (2019). Mammalian signaling circuits from bacterial parts. Nature Chemical Biology,
Yang X, Her J, Bashor CJ (2019). Mammalian signaling circuits from bacterial parts. Nature Chemical Biology,
Yang X, Her J, Bashor CJ (2019). Mammalian signaling circuits from bacterial parts. Nature Chemical Biology,
Heins ZJ, Mancuso CP, Kiriakov S, Wong BG, Bashor CJ, Khalili AS (2019). Designing automated, high-throughput, continuous cell growth experiments using eVOLVER. Journal of Visualized Experiments. 147: e59652
O'Connell RW, Bashor CJ (2019) The least mating pathway: synthetically refactoring a familiar signaling system for new applications. Cell. 177:521-3
Bashor CJ, Patel N, Choubey S, Beyzavi A, Kondev J, Collins JJ, Khalil AS (2019). Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies. Science. 364(6440): 593-7.
Perspective by Andrew H. Ng & Hana El-Samad in Science 363(6440): 531-2
Perspective by Andrew H. Ng & Hana El-Samad in Science 363(6440): 531-2
Wong BG, Mauso CP, Kiriakov S, Bashor CJ, Khalil AS. (2018) Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER. Nature Biotechnology. 36(7): 614-23